Cell

Global Untargeted Metabolomics for Discovery and Pathway Insights

Comprehensive metabolite profiling with high-resolution LC/GC-MS and AI-driven analysis to uncover biomarkers, classify samples, and map metabolic shifts.

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Untargeted Metabolomics

Unbiased Metabolite Profiling for Discovery and Insight

Unbiased Metabolite Profiling for Discovery and Insight
Untargeted metabolomics is an exploratory, hypothesis-generating approach that captures as many detectable metabolites as possible within a biological sample. Rather than relying on a predefined list of analytes, untargeted approach offers a comprehensive view of metabolic activity. It is the method of choice to discover novel disease biomarkers, understand metabolic shifts, and map pathway-level perturbations.

At Clarity Bio Systems, we combine high-resolution LC-MS/GC-MS platforms with our proprietary AI platform MSOne for data processing and statistical analysis to extract meaningful insights from complex, high-dimensional datasets. Our workflows are designed to handle complex biological matrices and deliver reproducible, high-quality data with maximum metabolome coverage.

Every project includes curated outputs and expert guidance from study design to pathway-level interpretation, ensuring your untargeted data translates into clear, biologically meaningful insights.

What you get

01

Curated Metabolite Tables

Clean, annotated datasets with feature intensities across all samples

02

High-Confidence Annotations

MS/MS spectral matches with confidence scores, library-backed annotations

03

Exploratory Statistics

PCA, volcano plots, clustering — uncover hidden patterns and group differences

04

Pathway Maps & Biological Interpretation

See which metabolic pathways are perturbed and why they matter

05

QC & Reproducibility Reports

Batch correction summaries, blank subtraction, and drift monitoring

06

Expert Consultation

Scientist-led review of results and next-step recommendations

Untargeted Panels

Untargeted Metabolomics is ideal for

Biomarker discovery and   exploratory profiling

Biomarker discovery and
exploratory profiling

Disease classification or   stratification

Disease classification or
stratification

Environmental and   exposomics research

Environmental and
exposomics research

Strain optimization in   synthetic biology

Strain optimization in
synthetic biology

Culture condition monitoring   and media optimization

Culture condition monitoring
and media optimization

Metabolic   fingerprinting   for quality assurance

Metabolic
fingerprinting
for quality assurance

Why choose Clarity for metabolomics

10,000+

Samples Analyzed

40+

Publications & patents

10+

Methods

30+

Clients & collaborators

500+

Metabolites

17

Completed Projects

10,000+

Samples Analyzed

40+

Publications & patents

10+

Methods

30+

Clients & collaborators

500+

Metabolites

17

Completed Projects

FAQs

The features depend upon the sample type. Each method detects more than 200 metabolites per ionization mode.

We annotate compounds using spectral libraries and retention index matches, and provide confidence scores following MSI guidelines. Confirmatory ID may require standards or follow-up studies.

We follow strict QC protocols and use AI-based normalization and batch correction to ensure cross-sample consistency.

Most untargeted projects are completed within 4-6 weeks, depending on scale and deliverables.

Launch Your Discovery Project

Connect with us to explore how untargeted metabolomics can uncover novel insights in your samples.