Cell

Quantitative Targeted Metabolomics for Biomarker and Process Validation

Accurate, reproducible metabolite quantification using validated LC/GC-MS panels, internal standards, and calibration curves — ready for regulatory or research use.

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Targeted Metabolomics

Focused quantitative metabolic insights

Focused quantitative metabolic insights
Targeted metabolomics is a quantitative approach that focuses on a predefined set of metabolites, delivering high sensitivity, specificity, and reproducibility. While untargeted approaches broadly survey the entire metabolome, targeted metabolomics delivers precise quantitative data that support hypothesis-driven research in academic, industrial, and diagnostic settings. It is the gold standard for validating biomarkers, assessing metabolic changes in response to treatments, and supporting regulatory or diagnostic applications.

At Clarity Bio Systems, we leverage validated LCMS and GCMS methods with robust internal standards and quality controls to deliver data you can trust. This approach is ideally suited for studies requiring analytical rigor, cross-sample consistency, and statistical reproducibility.

Every project includes curated outputs and expert guidance, from panel selection to data interpretation, ensuring your quantitative results are robust, reproducible, and ready for downstream decisions.

What you get

01

Instrumentation

TQ LC-MS/MS for detection of polar and thermolabile analytes

02

Validated Panels Available

Amino acids, vitamins, bile acids, short chain fatty acids

03

Custom Assay Development 

Built around your sample type and research goals

04

Quantitative Accuracy

Incorporates robust internal standards, calibration curves, and quality controls

05

Sample types supported

Plasma, serum, urine, tissue extracts, culture supernatants, cell lysates

Targeted Panels

Targeted Metabolomics is ideal for

Disease biomarker validation   in clinical or cohort studies

Disease biomarker validation
in clinical or cohort studies

Monitoring drug response   and toxicity

Monitoring drug response
and toxicity

Spent media analysis in   microbial and mammalian   cultures

Spent media analysis in
microbial and mammalian
cultures

Metabolic flux analysis and   isotope labeling studies

Metabolic flux analysis and
isotope labeling studies

Nutritional and metabolic   phenotyping

Nutritional and metabolic
phenotyping

Why choose Clarity for metabolomics

10,000+

Samples Analyzed

40+

Publications & patents

10+

Methods

30+

Clients & collaborators

500+

Metabolites

17

Completed Projects

10,000+

Samples Analyzed

40+

Publications & patents

10+

Methods

30+

Clients & collaborators

500+

Metabolites

17

Completed Projects

FAQs

Most panels quantify between 5 to 20 metabolites, depending on your research question. The available method panels are listed here. We can also develop custom methods for your compound of interest if you have the relevant standards available. Talk to us for more details. 

Yes. All targeted studies include quantification using calibration curves and internal standards.

Typically in the nanomolar to picomolar range, depending on compound class and matrix. The detection and quantification limit for every method panel will be provided to you upon request. 

Processed data, quantitative tables, and standard details.

Design Your Targeted Assay

Speak with our scientific team to scope your project and select or build the right metabolite panel.